Quantification of serine protease HtrA molecules secreted by the foodborne pathogen Campylobacter jejuni
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چکیده
منابع مشابه
Campylobacter jejuni--an emerging foodborne pathogen.
Campylobacter jejuni is the most commonly reported bacterial cause of foodborne infection in the United States. Adding to the human and economic costs are chronic sequelae associated with C. jejuni infection--Guillian-Barré syndrome and reactive arthritis. In addition, an increasing proportion of human infections caused by C. jejuni are resistant to antimicrobial therapy. Mishandling of raw pou...
متن کاملExpression of Helicobacter pylori Serine Protease HtrA in Campylobacter jejuni Reveals a Crucial
Aim: The gastrointestinal pathogens Helicobacter pylori and Campylobacter jejuni secrete serine protease HtrA into the extracellular space, where it cleaves the adherens junction protein E-cadherin. However, while htrA can be mutagenized in C. jejuni, htrA is an essential gene in H. pylori and rapid research progress on HtrA functions is hindered by the nonexistence of ΔhtrA deletion mutants in...
متن کاملCampylobacter jejuni : An emerging pathogen
Trachoo, N. Campylobacter jejuni : An emerging pathogen Songklanakarin J. Sci. Technol., 2003, 25(1) : 141-157 Campylobacter jejuni is a major cause of food-borne diarrhea in many countries. However, in some countries, a number of cases were undetected because of the inappropriate detection method and ignorance. Although C. jejuni usually does not cause death in health adults, it can be deadly ...
متن کاملMolecular methods to investigate adhesion, transmigration, invasion and intracellular survival of the foodborne pathogen Campylobacter jejuni.
Campylobacter jejuni is a spiral-shaped Gram-negative pathogen and major agent of gastrointestinal foodborne illness in humans worldwide. This pathogen encodes numerous described pathogenicity-associated factors involved in important processes including bacterial adhesion to, transmigration across, invasion into and intracellular survival within intestinal epithelial cells. This review article ...
متن کاملEditorial: About the Foodborne Pathogen Campylobacter
The name “Campylobacter” comes from ancient Greek meaning “curved rod” which describes the shape of this microorganism. Campylobacter was firstly isolated as a Vibrio species from epizootic ovine abortion in 1906 by McFadyean and Stockman (1913), and renamed in 1973 as the neotype strain Campylobacter after showing significant biological differences with Vibrio species (Véron and Chatelain, 197...
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ژورنال
عنوان ژورنال: Gut Pathogens
سال: 2019
ISSN: 1757-4749
DOI: 10.1186/s13099-019-0295-8